2-ETHYL-1,3-HEXANEDIOL
Human Health Effects:
Human Toxicity Excerpts:
... MODERATELY IRRITATING TO EYES, MUCOUS MEMBRANES, BUT NOT TO SKIN. INGESTION CAUSES
CNS DEPRESSION.
ONCE ABSORBED /THROUGH SKIN/ IT CAUSES /CNS DEPRESSION/ BUT LITTLE ORGANIC INJURY.
TWO HUNDRED TWENTY-THREE HUMAN VOLUNTEERS WERE PATCH TESTED FOR SENSITIZATION WITH THE
UNDILUTED PRODUCT. THREE ... DEVELOPED MILD SKIN REDDENING; OTHERWISE NO SIGNIFICANT SIGNS
OF SENSITIZATION OCCURRED.
WHEN TESTED AS A REPELLENT IN STICK FORMULATIONS CONTAINING SODIUM STEARATE, NONE
SHOWED SIGNS OF IRRITATION, SENSITIZATION, OR FATIGUING OF THE SKIN. /REPELLENT
FORMULATION CONTAINING SODIUM STEARATE/
ITS WIDESPREAD USE CONFIRMS ITS LACK OF HAZARD & IRRITANT PROPERTIES IN MAN.
Skin, Eye and Respiratory Irritations:
... MODERATELY IRRITATING TO EYES, MUCOUS MEMBRANES, BUT NOT TO SKIN.
Emergency Medical Treatment:
Emergency Medical Treatment:
| EMT Copyright Disclaimer: |
| Portions of the POISINDEX(R) database are provided here for general
reference. THE COMPLETE POISINDEX(R) DATABASE, AVAILABLE FROM MICROMEDEX, SHOULD BE
CONSULTED FOR ASSISTANCE IN THE DIAGNOSIS OR TREATMENT OF SPECIFIC CASES. Copyright
1974-1998 Micromedex, Inc. Denver, Colorado. All Rights Reserved. Any duplication,
replication or redistribution of all or part of the POISINDEX(R) database is a violation
of Micromedex' copyrights and is strictly prohibited. The following Overview, *** INSECT REPELLENTS ***, is relevant for this HSDB record chemical. |
| Life Support: |
o This overview assumes that basic life support measures
have been instituted.
|
| Clinical Effects: |
SUMMARY OF EXPOSURE
0.2.1.1 ACUTE EXPOSURE
o DEET - The most commonly used product in this class is
N,N-Diethyl-M-toluamide, commonly referred to as DEET.
Toxicity is primarily neurologic (encephalopathy,
seizures, movement disorders, coma) and may occur via
oral or dermal exposure, most commonly in children.
Fatalities from ingestion and chronic dermal
application of DEET containing products are rare, but
have been described.
o OTHER COMPOUNDS may include the following:
1. ETHYL HEXANEDIOL is only slightly absorbed across the
skin. However, it is moderately toxic on ingestion,
causing CNS depression, liver, and kidney injury.
2. INDALONE may cause slight skin irritation, plus kidney
and liver damage following protracted application to
the skin of animals.
3. DIMETHYL PHTHALATE has a low order of systemic
toxicity. When the volatilized esters are inhaled,
they are moderately irritating to the mucous
membranes. Extreme oral doses cause CNS depression in
animals.
4. N-OCTYL BICYCLOHEPTENE DICARBOXIMIDE is not irritating
to skin; extreme doses cause excitement, then
depression.
5. 2,3,4,5-BIS (2-BUTYLENE)TETRAHYDRO-2-FURALDEHYDE and
DI-N-PROPYL ISOCINCHOMERONATE have low systemic toxic
potential in mammals, and are not significantly
irritating.
6. N,N-DIETHYLPHENYLACETAMIDE (DEPA) - Hepatotoxic in
animals in large doses.
7. VEHICLES - Ethyl and isopropyl alcohols and freon used
as vehicles may contribute significantly to toxicity
of some formulations.
VITAL SIGNS
0.2.3.1 ACUTE EXPOSURE
o Hypotension after ingestion of DEET may occur.
HEENT
0.2.4.1 ACUTE EXPOSURE
o Eye exposure to DEET may result in a burning sensation.
A burning sensation of the lips, tongue and mouth may
be noted.
CARDIOVASCULAR
0.2.5.1 ACUTE EXPOSURE
o Bradycardia is rare but has been reported after dermal
exposure to DEET. Hypotension has been reported after
large oral ingestions.
NEUROLOGIC
0.2.7.1 ACUTE EXPOSURE
o Confusion, ataxia, hypertonicity, and clonic jerking
progressing to coma and seizures may occur after acute
oral or chronic dermal exposure to DEET.
GASTROINTESTINAL
0.2.8.1 ACUTE EXPOSURE
o Abdominal pain, nausea and vomiting may develop after
excessive dermal exposure to DEET.
HEPATIC
0.2.9.1 ACUTE EXPOSURE
o Toxic hepatitis may occur after DEET exposure.
DERMATOLOGIC
0.2.14.1 ACUTE EXPOSURE
o Contact urticaria may develop after DEET use. A
bullous eruption in the antecubital and popliteal
fossae that may progress to painful skin necrosis and
permanent scarring has been described after DEET use.
o 2-ETHYL-1,3-HEXANEDIOL is a skin irritant, erythema may
develop after dermal application.
PSYCHIATRIC
0.2.18.1 ACUTE EXPOSURE
o Acute paranoid psychosis from repeated dermal
application of diethyltoluamide has been reported.
IMMUNOLOGIC
0.2.19.1 ACUTE EXPOSURE
o Anaphylaxis has been reported after topical DEET
application.
|
| Laboratory: |
o Plasma levels of these agents may help to confirm the
diagnosis, but toxic levels have yet to be established.
o Monitor liver and renal function tests carefully in
symptomatic patients.
o Consider CT and lumbar puncture in patients with
neurologic effects to rule out other causes.
|
| Treatment Overview: |
ORAL EXPOSURE
o Coma and seizures can occur rapidly following ingestion
of DEET, within 30 minutes to one hour of ingestion.
Ipecac-induced emesis is not recommended.
1. Cautious lavage with a small-bore soft nasogastric
tube, using small aliquots of water or saline, may be
indicated since the risk of sequelae from absorption of
DEET is high. Activated charcoal should be instilled
before removal of the tube.
o ACTIVATED CHARCOAL: Administer charcoal as slurry (240
mL water/30 g charcoal). Usual dose: 25 to 100 g in
adults/adolescents, 25 to 50 g in children (1 to 12
years), and 1 g/kg in infants less than 1 year old.
o SEIZURES: Administer a benzodiazepine IV; DIAZEPAM
(ADULT: 5 to 10 mg, repeat every 10 to 15 min as
needed. CHILD: 0.2 to 0.5 mg/kg, repeat every 5 min
as needed) or LORAZEPAM (ADULT: 4 to 8 mg; CHILD: 0.05
to 0.1 mg/kg).
1. Consider phenobarbital if seizures recur after diazepam
30 mg (adults) or 10 mg (children > 5 years).
2. Monitor for hypotension, dysrhythmias, respiratory
depression, and need for endotracheal intubation.
Evaluate for hypoglycemia, electrolyte disturbances,
hypoxia.
o NATIONAL PESTICIDE TELECOMMUNICATIONS NETWORK:
1. Provides consultation to poison centers and other
health professionals for the management of pesticide
poisoning. Calls regarding emergency cases requiring
immediate medical response will be transferred to the
Oregon Poison Center. The National Pesticide
Telecommunications Network has a toll-free number,
1-800-858-7378, or if outside the U.S., the
non-toll-free number is 541-737-6094. Hours are 6:30
AM to 4:30 PM Pacific time 7 days/week excluding
holidays. FAX: 1-541-737-0761. email:
nptn@ace.orst.edu
INHALATION EXPOSURE
o INHALATION: Move patient to fresh air. Monitor for
respiratory distress. If cough or difficulty breathing
develops, evaluate for respiratory tract irritation,
bronchitis, or pneumonitis. Administer oxygen and
assist ventilation as required. Treat bronchospasm with
beta2 agonist and corticosteroid aerosols.
EYE EXPOSURE
o DECONTAMINATION: Irrigate exposed eyes with copious
amounts of tepid water for at least 15 minutes. If
irritation, pain, swelling, lacrimation, or photophobia
persist, the patient should be seen in a health care
facility.
DERMAL EXPOSURE
o Wash affected areas twice with copious amounts of soap
and water. Alcohol-detergent solutions such as "green
soap" are most efficient for this purpose. A physician
may need to examine the exposed area if irritation or
pain persist after the area is washed.
|
| Range of Toxicity: |
o Ingestion of 25 mL of 50% DEET by a one-year-old child
resulted in severe toxicity.
o Ingestion of 50 mL of 100% DEET by adolescents or adults
has resulted in severe toxicity, and death.
o Extensive daily dermal application of 10 to 15% DEET for 2
days to 3 months has resulted in encephalopathy in
children.
|
Animal Toxicity Studies:
Non-Human Toxicity Excerpts:
... WHEN RABBITS WERE INUNCTED DAILY FOR 90 DAYS, 2 ML/KG (1.88 G/KG) CAUSED ABOUT 50%
MORTALITY, & SOMEWHAT GREATER MORTALITY RESULTED @ ... 4 ML/KG (3.76 G/KG). CONTINUED
CONTACT CAUSED...IRRITATION TO SKIN ... & ANIMALS THAT DIED EXHIBITED MODERATE LIVER
& KIDNEY INJURY. LEUKOCYTOSIS WAS OBSERVED IN ONLY 1 ANIMAL TREATED AT THE 4 ML/KG ...
LEVEL.
... RATS WERE FED UP TO 2 YR ON DIETS CONTAINING 2.0, 4.0, & 8.0% OF
2-ETHYL-1,3-HEXANEDIOL. GROWTH WAS DEPRESSED @ ALL LEVELS. AT 8% LEVEL, ALL ANIMALS WERE
DEAD WITHIN 18 WK ... DUE TO INANITION. THOSE @ 4.0 & 2.0% LEVELS SURVIVED, &
AUTOPSY REVEALED NO ORGANIC INJURY ATTRIBUTABLE TO THE GLYCOL.
... RATS FED FOR 90 DAYS ON DIET THAT PROVIDED DAILY INTAKE OF 0.70 G/KG ... DID NOT
GROW AS WELL AS CONTROLS, BUT ... SUFFERED NO ORGANIC INJURY. WHEN ... MAINTAINED ON ...
DAILY INTAKE OF 0.48 G/KG, GROWTH WAS NORMAL & NO DETECTABLE ADVERSE EFFECTS ...
NOTED.
RATS EXPOSED TO ESSENTIALLY SATURATED VAPORS GENERATED AT ROOM TEMPERATURE FOR 2 HR
SURVIVED; THOSE EXPOSED FOR 8 HR DIED. THE RATS EXPOSED TO A MIST GENERATED @ 170 DEG C
FOR 2 HR ALSO SURVIVED WHEREAS THOSE EXPOSED FOR 8 HR DIED. THOSE EXPOSED TO A FOG
GENERATED AT 70 DEG C WITH A NEBULIZER AT A CONCN ESTIMATED TO BE 4800 PPM FOR 8 HR ALL
SURVIVED.
SKIN SENSITIZATION: GUINEA PIGS WERE NOT SENSITIZED BY 2-ETHYL-1,3-HEXANEDIOL
/IN RATS/ ... LARGE /ORAL/ DOSES ... APPEARS TO CAUSE DEEP /SRP: CNS DEPRESSION/ ...
& THIS IS BELIEVED TO BE THE CAUSE OF DEATH.
TESTS WERE DONE IN WHICH THE BELLY OF A RABBIT WAS COVERED WITH A REPELLENT-TREATED NET
& THEN EXPOSED TO INSECTS. 2-ETHYL-1,3-HEXANEDIOL & TETRAHYDROFURFURYL OCTANOATE
WERE NOT EFFECTIVE REPELLENTS AGAINST INSECTS FOR 1 HR COMPARED WITH BIOALLETHRIN &
1-(CYCLOHEXYLCARBONYL)HEXAHYDRO-1H-AZEPINE).
A COMPOSITION WAS PREPARED CONTAINING P-TOLUENESULFONAMIDE 75%, 2-ETHYL-1,3-HEXANEDIOL
20%, & PARAPLEX G25 5%. THIS COMPOSITION EXHIBITED IN VITRO ANTIBACTERIAL &
ANTIFUNGAL ACTIVITY.
Ethylhexanediol rated 5 /on scale of 1 to 10 with 10 being the most severe/ on rabbit
eyes.
To evaluate the developmental toxicity potential of 2-ethyl-1,3-hexanediol,
timed-pregnant CD rats were treated daily during organogenesis (gestational days 6-15)
with 2-ethyl-1,3-hexanediol by occluded cutaneous application. Doses of 1.0, 2.0 or 4.0
ml/kg/day were administered for six hours per day. ... On gestational day 21, maternal
effects at 4.0 ml/kg/day were limited to increased absolute and relative liver weights.
Relative liver weights were also increased at 2.0 and 1.0 ml/kg/day. In fetuses at 4.0
ml/kg/day, the incidence of a single visceral malformation (hydroureter) was increased.
Three visceral variations (atelectasis, partial atelectasis, dilated lateral ventricles)
and 12 skeletal variations, indicative of reduced ossification, were also observed at 4.0
ml/kg/day. The incidence of dilated lateral ventricles was increased in fetuses at 2.0
ml/kg/day. Maternal toxicity was not observed in dams at doses up to 4.0 ml/kg/day;
evidence of developmental delay at 2.0 and 4.0 ml/kg/day suggests that
2-ethyl-1,3-hexanediol is a mild developmental toxicant when administered cutaneously to
pregnant CD rats.
Non-Human Toxicity Values:
LD50 Rat oral 1400 mg/kg
LD50 Mouse oral 1900 mg/kg
Metabolism/Pharmacokinetics:
Metabolism/Metabolites:
... UNABLE TO DETECT ANY METABOLITES ... WHEN ... FED TO RABBITS.
Absorption, Distribution & Excretion:
TOPICAL & IV APPLICATIONS OF (14)C LABELED 2-ETHYL-1,3-HEXANEDIOL WERE MADE TO
HAIRLESS DOGS. AFTER TOPICAL ADMIN, EXCRETION WAS NEARLY COMPLETE AFTER 4-5 DAYS.
RADIOACTIVITY LEVELS IN BLOOD SAMPLES WERE TOO LOW TO BE ACCURATELY MEASURED. WITHIN 48-96
HR AFTER APPLICATION ONLY SMALL AMT OF RADIOACTIVITY WAS RECOVERED FROM SKIN. RATE OF
URINARY EXCRETION AFTER IV ADMIN WAS COMPARABLE TO THAT RECORDED IN HUMANS. IT IS
SUGGESTED THAT PERMEABILITY OF HAIRLESS DOG'S SKIN MAY BE QUITE SIMILAR TO THAT OF HUMAN
SKIN.
AN IN VITRO APPARATUS WAS USED TO STUDY SKIN EVAPORATION & PENETRATION OF MOSQUITO
REPELLENTS. IN VITRO REPELLENT DURATION, CALCULATED FROM REPELLENT EVAPORATION RATES, WAS
COMPARED TO IN VIVO DURATION AT THE SAME DOSE (0.3 MG/SQ CM) TO ASSESS VALIDITY OF THE
MODEL. IN VITRO DURATIONS FOR 2-ETHYL-1,3-HEXANEDIOL CORRELATED WITH IN VIVO DURATIONS,
ALTHOUGH IN VITRO DURATION WAS LONGER THAN IN VIVO DURATION.
PERCENTAGE PENETRATION OF 2-ETHYL-1,3-HEXANEDIOL WAS DETERMINED ON HAIRLESS DOGS AT 4
UG/SQ CM. MEAN PERCENTAGE PENETRATION INCREASED SLIGHTLY WITH INCREASED DOSE OF
2-ETHYL-1,3-HEXANEDIOL, BUT NONE OF THESE CHANGES DIFFERED SIGNIFICANTLY AT THE 95%
CONFIDENCE LEVEL.
Interactions:
SUCKER CONTROL IN TOBACCO WAS EXHIBITED BY 5% 2-ETHYL-1,3-HEXANEDIOL BY ITSELF, &
ESPECIALLY WHEN COMBINED WITH MALEIC HYDRAZIDE.
Pharmacology:
Interactions:
SUCKER CONTROL IN TOBACCO WAS EXHIBITED BY 5% 2-ETHYL-1,3-HEXANEDIOL BY ITSELF, &
ESPECIALLY WHEN COMBINED WITH MALEIC HYDRAZIDE.
Environmental Fate & Exposure:
Environmental Standards & Regulations:
Chemical/Physical Properties:
Molecular Formula:
C8-H18-O2
Molecular Weight:
146.22
Color/Form:
SLIGHTLY OILY LIQ
COLORLESS LIQUID
Odor:
ODORLESS
Boiling Point:
244.2 DEG C @ 760 MM HG
Melting Point:
-40 DEG C
Density/Specific Gravity:
0.9325 @ 22 DEG C/4 DEG C
Solubilities:
SOL IN WATER 0.6% WT/WT; SOLUBILITY OF WATER IN ETHOHEXADIOL
10.8% WT/WT; SOL IN ETHANOL, ISOPROPANOL, PROPYLENE GLYCOL, CASTOR OIL
MISCIBLE WITH CHLOROFORM, DIETHYL ETHER
Spectral Properties:
INDEX OF REFRACTION: 1.4530 @ 22 DEG C/D
IR: 4226 (Sadtler Research Laboratories Prism Collection)
NMR: 17304 (Sadtler Research Laboratories Spectral Collection)
MASS: 841 (Atlas of Mass Spectral Data, John Wiley & Sons, New York)
Vapor Density:
5.03
Vapor Pressure:
LESS THAN 0.01 MM HG @ 20 DEG C
Viscosity:
323 CENTIPOISES @ 20 DEG C
Other Chemical/Physical Properties:
FAINT ODOR OF WITCH HAZEL; DISTILLATION RANGE 241-249 DEG C; DENSITY: 0.939-0.943 @ 20
DEG C/20 DEG C /CRUDE/
BOTH HYDROXY GROUPS CAN BE ESTERIFIED, THE SECONDARY GROUP WITH DIFFICULTY
HYGROSCOPIC; 7.8 LB/GAL @ 20 DEG C
ABSOLUTE VISCOSITY: 271 CENTIPOISES
Chemical Safety & Handling:
Skin, Eye and Respiratory Irritations:
... MODERATELY IRRITATING TO EYES, MUCOUS MEMBRANES, BUT NOT TO SKIN.
NFPA Hazard Classification:
Health: 1. 1= Materials only slightly hazardous to health. It may be desirable to wear
self-contained breathing apparatus.
Flammability: 1. 1= Materials that must be preheated before ignition can occur. Water
may cause frothing of liquids ... if it gets below the surface of the liquid and turns to
steam. ... water spray gently applied to the surface will cause a frothing which will
extinguish the fire.
Reactivity: 0. 0= Materials which are normally stable even under fire exposure
conditions, and which are not reactive with water. Normal fire fighting procedures may be
used.
Flash Point:
230 DEG F (110 DEG C) (OPEN CUP)
Autoignition Temperature:
635 DEG F (335 DEG C)
Fire Fighting Procedures:
WATER OR FOAM MAY CAUSE FROTHING. "ALCOHOL" FOAM.
Preventive Measures:
SRP: The scientific literature for the use of contact lenses in industry is
conflicting. The benefit or detrimental effects of wearing contact lenses depend not only
upon the substance, but also on factors including the form of the substance,
characteristics and duration of the exposure, the uses of other eye protection equipment,
and the hygiene of the lenses. However, there may be individual substances whose
irritating or corrosive properties are such that the wearing of contact lenses would be
harmful to the eye. In those specific cases, contact lenses should not be worn. In any
event, the usual eye protection equipment should be worn even when contact lenses are in
place.
Stability/Shelf Life:
STABLE UNDER NORMAL STORAGE CONDITIONS
Occupational Exposure Standards:
Manufacturing/Use Information:
Major Uses:
SOLVENT FOR RESINS & INKS; PLASTICIZER; CHEM INTERMEDIATE IN PRODN OF POLYURETHANE
RESINS
INSECT REPELLENT, COSMETICS; VEHICLE AND SOLVENT IN PRINTING INKS, MEDICINE, CHELATING
AGENT FOR BORIC ACID
Manufacturers:
Union Carbide Corporation, Hq, Old Ridgeway Road, Danbury, CT 06817, (203) 794-2000;
Chemicals and Plastics Business Group; Specialty Chemicals Division; Production site:
South Charleston, WV 25303
Methods of Manufacturing:
PREPD BY CATALYTIC TRIMOLECULAR CONDENSATION OF BUTYRALDEHYDE WITH MAGNESIUM ALUMINUM
ETHOXIDE YIELDING THE MONOBUTYRATE OF 2-ETHYL-1,3-HEXANEDIOL, FOLLOWED BY HYDROLYSIS OF
THE ESTER.
... PRODUCED COMMERCIALLY BY HYDROGENATION OF BUTYRALDOL
(2-ETHYL-3-HYDROXYCAPROALDEHYDE).
General Manufacturing Information:
FORMULATED PRODUCT DISCONTINUED BY UNION CARBIDE AGRICULTURAL PRODUCTS CO, INC.
... EXTENSIVE MILITARY USE HAS INDICATED ITS SAFETY & LACK OF IRRITANT PROPERTIES.
A COMPOSITION WAS PREPARED CONTAINING P-TOLUENESULFONAMIDE 75%, 2-ETHYL-1,3-HEXANEDIOL
20%, & PARAPLEX G25 5%.
Formulations/Preparations:
WIDELY USED IN MIXTURE (2 PARTS) WITH DIMETHYL PHTHALATE (6 PARTS) & INDALONE (2
PARTS).
GRADES: USP (AS ETHOHEXADIOL); INDUSTRIAL
Laboratory Methods:
Analytic Laboratory Methods:
ETHYL HEXANEDIOL GIVES A COLORED CMPD UPON
REACTION WITH CONCN SULFURIC ACID & P-DIMETHYLAMINOBENZALDEHYDE WHICH IS DETERMINED AT
500 NM.
Special References:
Synonyms and Identifiers:
Synonyms:
6-12
**PEER REVIEWED**
CARBIDE 6-12
**PEER REVIEWED**
COMPOUND 6-12 INSECT REPELLANT
**PEER REVIEWED**
ENT 375
**PEER REVIEWED**
EPA Pesticide Chemical Code 041001
**PEER REVIEWED**
Ethohexadiol
**PEER REVIEWED**
Ethylhexanediol
**PEER REVIEWED**
2-ETHYLHEXANEDIOL-1,3
**PEER REVIEWED**
ETHYL HEXYLENE GLYCOL
**PEER REVIEWED**
2-ETHYL-1,3-HEXYLENE GLYCOL
**PEER REVIEWED**
2-ETHYL-3-PROPYL-1,3-PROPANEDIOL
**PEER REVIEWED**
1,3-HEXANEDIOL, 2-ETHYL-
**PEER REVIEWED**
3-HYDROXYMETHYL-N-HEPTAN-4-OL
**PEER REVIEWED**
6-12 INSECT REPELLENT
**PEER REVIEWED**
LATKA 612 (Czechoslovakia)
**PEER REVIEWED**
OCTYLENE GLYCOL
**PEER REVIEWED**
REPELLANT 612
**PEER REVIEWED**
RUTGERS 6-12
**PEER REVIEWED**
RUTGERS 612
**PEER REVIEWED**
Formulations/Preparations:
WIDELY USED IN MIXTURE (2 PARTS) WITH DIMETHYL PHTHALATE (6 PARTS) & INDALONE (2
PARTS).
GRADES: USP (AS ETHOHEXADIOL); INDUSTRIAL
RTECS Number:
NIOSH/MO2625000
Administrative Information:
Hazardous Substances Databank Number: 1716
Last Revision Date: 20010809
Last Review Date: Reviewed by SRP on 08/07/1991
Update History:
Complete Update on 08/09/2001, 1 field added/edited/deleted.
Complete Update on 06/12/2000, 1 field added/edited/deleted.
Complete Update on 02/02/2000, 1 field added/edited/deleted.
Complete Update on 09/21/1999, 1 field added/edited/deleted.
Complete Update on 08/26/1999, 1 field added/edited/deleted.
Complete Update on 03/19/1999, 1 field added/edited/deleted.
Complete Update on 06/02/1998, 1 field added/edited/deleted.
Complete Update on 03/31/1998, 3 fields added/edited/deleted.
Field Update on 02/27/1998, 1 field added/edited/deleted.
Field Update on 10/23/1997, 1 field added/edited/deleted.
Field Update on 09/17/1997, 1 field added/edited/deleted.
Field Update on 05/08/1997, 1 field added/edited/deleted.
Field Update on 05/01/1997, 2 fields added/edited/deleted.
Complete Update on 10/15/1996, 1 field added/edited/deleted.
Complete Update on 01/21/1996, 1 field added/edited/deleted.
Complete Update on 12/28/1994, 1 field added/edited/deleted.
Complete Update on 03/25/1994, 1 field added/edited/deleted.
Field update on 12/21/1992, 1 field added/edited/deleted.
Complete Update on 12/18/1991, 35 fields added/edited/deleted.
Complete Update on 10/10/1990, 1 field added/edited/deleted.
Complete Update on 04/16/1990, 1 field added/edited/deleted.
Field update on 12/29/1989, 1 field added/edited/deleted.
Complete Update on 12/26/1984
Record Length: 39486